1. About clotrimazole

Clotrimazole is an antifungal medicine.

It's used to treat skin infections caused by a fungus (yeast).

Clotrimazole treats different types of fungal infections including:

If you're looking for information on treating thrush, read clotrimazole for thrush.

Clotrimazole is available as a cream, spray and a solution that you put on your skin. The treatment you use will depend on where the infection is on your body.

You can buy clotrimazole from a pharmacy or supermarket.

2. Key facts

  • It usually takes 7 days for fungal infections to improve.
  • Apply clotrimazole to the infected area 2 or 3 times a day for at least 2 weeks.
  • The most common side effect of clotrimazole is irritation in the area where you apply the treatment.
  • Clotrimazole is also known by the brand name Canesten.

3. Who can and cannot use clotrimazole

Clotrimazole cream, spray and solution can be used by most adults and children.

Clotrimazole is not suitable for everyone. To make sure it's safe for you, tell a doctor if you have ever had an allergic reaction to clotrimazole or any other medicines in the past.

4. How and when to use clotrimazole

How long you use clotrimazole for depends on the type of infection you have.

It's best to use it for at least 2 weeks, even if all signs of the infection have gone, to stop it from coming back. It can be used for up to 4 weeks if needed.

Apply clotrimazole to the affected area 2 to 3 times a day. It will work better if you use it 3 times a day.

If the affected area is large or hairy, it's best to use either the spray or solution.

If you're using clotrimazole on your feet, make sure you wash and thoroughly dry your feet, especially between your toes, before applying clotrimazole.

How to use clotrimazole cream

Apply clotrimazole cream to the affected area. Use the cream on your skin only. A strip of cream (0.5cm long) is enough to treat an area the size of your hand. Avoid putting it near your mouth, lips and eyes.

How to use clotrimazole spray

If you're using the spray for the first time, prepare the spray by pressing the spray head down once or twice.

Hold and spray about 15cm away from the affected area.

How to use clotrimazole solution

The solution comes in a bottle with a plastic "dropper" which lets the solution out in drops.

Apply clotrimazole solution thinly and evenly to the affected areas.

A few drops of clotrimazole solution should be enough to cover an area the size of a hand.

If your ear is infected, put 2 to 3 drops of clotrimazole solution into your ear.

What if I forget to use it?

If you forget to use your treatment, do not worry. Just apply it as soon as you remember and then keep following your usual routine.

What if I use too much?

If you use too much clotrimazole cream, spray or solution or use it more often than you need to, it may make your skin red or irritated. If this happens, use less the next time.

5. Side effects

Like all medicines, clotrimazole can cause side effects, although not everyone gets them. Side effects usually go away when you stop using it.

Common side effects

Talk to a pharmacist or doctor if these side effects bother you or do not go away:

  • red, irritated skin
  • pain or a burning or stinging sensation

If the side effects do not go away, try using a smaller amount of the treatment or stop using it completely.

Serious allergic reaction

In rare cases, it's possible to have a serious allergic reaction (anaphylaxis) to clotrimazole.

These are not all the side effects of clotrimazole. For a full list, see the leaflet inside your medicine packet.


You can report any suspected side effect to the UK safety scheme.

6. Pregnancy and breastfeeding

Clotrimazole is generally considered safe to use during pregnancy.

Find out more about how clotrimazole can affect you and your baby during pregnancy by Best Use of Medicines in Pregnancy (BUMPS).

Clotrimazole and breastfeeding

Clotrimazole is generally considered safe to use while you're breastfeeding.

If your baby is being treated for oral thrush you can carry on breastfeeding but you'll need to be treated at the same time. Apply clotrimazole cream on and around your nipples after each time you breastfeed your baby.


Tell a pharmacist or doctor if you're trying to get pregnant, are already pregnant or if you're breastfeeding.

7. Caution with other medicines

Some medicines can affect the way clotrimazole works. They can also make you more likely to get side effects.

Tell a doctor before using clotrimazole if you are using Sofradex ear drops. Do not use these in your ear at the same time as clotrimazole.

Mixing clotrimazole with herbal remedies and supplements

There's very little information about taking herbal remedies and supplements while using clotrimazole.


For safety, tell a pharmacist or doctor if you're taking any other medicines, including herbal remedies, vitamins or supplements.

8. Common questions

Useful resources

Page last reviewed: 16/09/2019
Next review due: 16/09/2022