1. About docusate

Docusate is a laxative that is used to treat constipation (difficulty pooing). It helps to soften your poo and makes your bowel movements easier.

It is helpful when you have difficulty going to the toilet because of dry poos or piles (haemorrhoids) or if you have a tear in the lining of your anus (an anal fissure).

You may also be given docusate if you're going to have an x-ray of your stomach. It can help you empty your bowels beforehand.

Docusate comes as capsules and as a liquid that you swallow. It also comes as an enema – a tube of liquid medicine which you squeeze into your anus.

Docusate is available on prescription. You can also buy it from pharmacies.

2. Key facts

  • Docusate capsules and liquid take 1 or 2 days to work.
  • The enema usually works within 20 minutes – so it's best to stay close to a toilet.
  • Do not give docusate to a child under 12 years old unless their doctor prescribes it.
  • Do not take it for more than a week without talking with your doctor.

3. Who can and cannot take docusate

Most adults can safely take docusate, but do not give it to a child under 12 years old unless their doctor prescribes it.


Never give docusate to a child under 12 years old unless their doctor prescribes it.

Docusate is not suitable for some people. To make sure it is safe for you, tell your doctor or pharmacist if you have:

  • ever had an allergic reaction to docusate or any other medicines in the past
  • ever had an allergic reaction to fructose or sorbitol (types of sugar)
  • a blockage in your gut (intestine)
  • stomach pains
  • been feeling sick in the last 24 hours or have been sick
  • been taking a mineral oil laxative such as liquid paraffin

Do not use an enema containing docusate if you have:

4. How and when to take docusate

Docusate comes as capsules, liquid and an enema.

How to take it

  • Capsules – swallow the capsule whole with plenty of water.
  • Liquid – this comes with a plastic cup or spoon to measure the dose. Do not use a kitchen spoon as it will not give the right amount. If you do not have a cup or spoon, ask your pharmacist for one. When you've swallowed it, drink plenty of water or another drink, such as milk or orange juice.
  • Enema – squeeze the tube of liquid gently into your anus. The information leaflet which comes with your docusate will explain how to do this.

Docusate does not usually upset your stomach. You can take the capsules or liquid with or without food. Try to take them at regular intervals throughout the day. Mealtimes (breakfast, lunch and dinner) are useful reminders.

There is no specific time of day to use an enema but it works quickly (usually between 5 and 20 minutes), so use it when you know you'll be near a toilet.

How much to take

  • Capsules – the normal dose is 1 capsule 3 times a day. Do not take more than 5 capsules in a day.
  • Liquid – the normal dose is 2 or 3 x 5ml spoonfuls. Take this dose 3 times a day.
  • Enema – normally 1 tube of liquid is all you need. If you need a second dose, you can use it later in the day or the next day.

You should feel more comfortable within 1 or 2 days of treatment. Reduce the dose as your condition gets better.

Drink plenty of fluids (6 to 8 glasses a day) while you are taking docusate or your constipation may get worse.

What if I forget to take it?

If you forget a dose of docusate, do not worry, just take the next dose as normal.

Never take 2 doses at the same time. Never take an extra dose to make up for a forgotten one.

What if I take too much?

Taking an extra dose of docusate is unlikely to harm you but you should drink lots of water. You may get diarrhoea and stomach pain but this should get better within 1 or 2 days.

If you're worried, talk to your doctor or pharmacist for advice.

5. Side effects

Like all medicines, docusate may cause side effects in some people but most people have no side effects or only minor ones.

Common side effects

If you get any of these side effects, talk to your doctor or pharmacist:

  • feeling sick (nausea)
  • diarrhoea
  • stomach cramps

These side effects are mild and usually go away after a couple of days.

With the docusate enema sometimes people get a burning or pain around their anus. Occasionally the wall of the anus may bleed. This is a reaction to the enema and it should clear up quickly. If the pain or bleeding does not go away or you are worried about them, talk to your doctor or pharmacist.

Serious side effects

In rare cases, it's possible to have a serious allergic reaction (anaphylaxis) to docusate.

These are not all the side effects of docusate. For a full list see the leaflet inside your medicines packet.


7. How to cope with side effects of docusate

What to do about:

  • feeling sick – try taking docusate with meals or mixing your dose with some water or fruit juice.
  • diarrhoea – drink plenty of water or other fluids. It may also help to take an oral rehydration drink to prevent dehydration. You can buy sachets of powder from a pharmacy which you mix with water. Reducing the dose of docusate may also help diarrhoea. Do not take any other medicines to treat diarrhoea without speaking to a pharmacist or doctor.
  • stomach cramps – if you get stomach cramps, reduce your dose of docusate until it goes away.

8. Pregnancy and breastfeeding

Docusate may not be suitable if you're pregnant or breastfeeding because small amounts might be absorbed by your gut.

If you're pregnant or breastfeeding, it's always better to try to treat constipation without taking a medicine. Your doctor or midwife will first advise you to eat more fibre and drink plenty of fluids. It may also help to do gentle exercise.

If diet and lifestyle changes do not work, your doctor or midwife may recommend a laxative, such as lactulose or Fybogel. These are safer laxatives to take during pregnancy and while breastfeeding.

9. Cautions with other medicines

Do not take docusate with a mineral oil laxative such as liquid paraffin.

Mixing docusate with herbal remedies and supplements

There's very little information about taking herbal remedies and supplements with docusate.

10. Common questions about docusate

Page last reviewed: 29/01/2018
Next review due: 29/01/2021