Buscopan (hyoscine butylbromide)


1. About Buscopan

Buscopan relieves painful stomach cramps, including those linked with irritable bowel syndrome (IBS).

It can also help bladder cramps and period pain.

Buscopan contains the active ingredient hyoscine butylbromide.

It's not the same as hyoscine hydrobromide, which is a different medicine taken to prevent motion sickness.

Buscopan comes as tablets and is available on prescription. Buscopan also comes as 2 different products that you can buy from a pharmacy or shop:

  • Buscopan Cramps
  • Buscopan IBS Relief

It can also be given by injection, but this is usually only done in hospital.


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3. Key facts

  • Buscopan relieves the pain of stomach cramps by helping your gut to relax.
  • The medicine works very quickly. Painful cramps should ease within 15 minutes.
  • It's unusual to have any side effects, but some people get a dry mouth, constipation and blurred vision.
  • Buscopan comes on prescription and as 2 different products (Buscopan IBS Relief and Buscopan Cramps) that you can buy from a pharmacy or shop.
  • If you're self-treating with Buscopan, do not take it for longer than 2 weeks without checking with a doctor.

4. Who can and cannot take Buscopan

Most adults and children from 6 years of age can take Buscopan.

Only take Buscopan IBS Relief tablets if your doctor has said that you have irritable bowel syndrome.

Giving Buscopan to children

Do not give Buscopan Cramps tablets to children under the age of 6 years.

Do not give Buscopan IBS Relief tablets to children under the age of 12 years.

Buscopan is not suitable for some people.

Check with your doctor or pharmacist before taking Buscopan if you:

  • ever had an allergic reaction to Buscopan or any other medicine
  • a rare type of glaucoma called acute angle closure glaucoma (Buscopan can increase the pressure in the eye and make your glaucoma worse)
  • a very enlarged bowel
  • myasthenia gravis (a condition where the muscles become weak and tire easily)
  • a condition where your bowel is blocked and does not work properly, such as paralytic ileus
  • are 40 years or over
  • are pregnant, trying to get pregnant or breastfeeding
  • have recently passed blood in your poo
  • are feeling or being sick (nausea or vomiting)
  • have lost your appetite or lost weight
  • are feeling tired and looking paler than usual
  • have unusual vaginal bleeding or vaginal discharge
  • think you may have food poisoning (especially if you have recently travelled abroad)
  • have a very fast heart rate or any other heart problems
  • have difficulty or pain when peeing (for example, men with prostate problems)
  • have an overactive thyroid
  • have a high temperature
  • have digestive problems such as heartburn and acid reflux, severe constipation or ulcerative colitis

5. How and when to take Buscopan

Always follow the advice of your doctor or pharmacist or the instructions that come with Buscopan.

Dosage and strength

Each Buscopan tablet contains 10mg of hyoscine butylbromide. Buscopan tablets are all the same strength whether you get them on prescription or whether you buy them as Buscopan Cramps or Buscopan IBS Relief.

The usual dose of Buscopan for stomach cramps (or cramping pain) in adults and children aged 12 years and over is 2 tablets, taken 4 times a day.

For children aged 6 to 11 years, the usual dose is 1 tablet, taken 3 times a day.

The usual dose of Buscopan for symptoms of irritable bowel syndrome (IBS) diagnosed by a doctor in adults and children aged 12 years and over is 1 tablet, taken 3 times a day. You can increase this to 2 tablets, taken 4 times a day if needed.

When to take Buscopan

Take Buscopan tablets when you have stomach cramps or period pain.

Buscopan does not usually upset your stomach, so you can take it with or without food.

Only take Buscopan IBS Relief if a doctor has confirmed that you have IBS.

What if I forget to take it?

If you forget to take a dose, take it as soon as you remember. If you do not remember until it's nearly time for the next dose, skip the missed dose and take the next one at the usual time.

Never take 2 doses at the same time. Never take an extra dose to make up for a forgotten one.

If you often forget doses, it may help to set an alarm to remind you. You could also ask your pharmacist for advice on other ways to remember to take your medicines.

What if I take too much?

If you take an extra dose of Buscopan, it's unlikely to harm you.

Speak to your pharmacist or doctor if you're worried, or if you have taken more than 1 extra dose.


6. Side effects

Like all medicines, Buscopan can cause side effects in some people, but most people have no side effects or only minor ones.

Common side effects

These side effects happen in more than 1 in 100 people.

Talk to your doctor or pharmacist if these side effects bother you or do not go away:

  • dry mouth
  • constipation
  • blurred vision
  • fast heart rate

Serious side effects

It happens rarely, but some people may have a serious side effect when taking Buscopan.

Stop taking Buscopan and call a doctor straight away if you:

  • get a painful red eye with loss of vision (this could be caused by increased pressure in your eye)
  • find it hard to pee

Serious allergic reaction

In rare cases, it's possible to have a serious allergic reaction (anaphylaxis) to Buscopan.

These are not all the side effects of Buscopan. For a full list, see the leaflet inside your medicine packet.


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8. How to cope with side effects of Buscopan

What to do about:

  • dry mouth – chew sugar-free gum or suck sugar-free sweets
  • constipationget more fibre into your diet, such as fresh fruit, vegetables and cereals, and drink plenty of water. Try to exercise more regularly, for example, by going for a daily walk or run. If this does not help, talk to your pharmacist or doctor.
  • blurred vision – do not drive or ride a bike until you can see clearly again. Do not take your next dose of Buscopan if your vision is still blurry. Speak to your doctor or pharmacist if your vision has not returned to normal a day after taking your last dose.
  • fast heart rate – if this happens regularly after taking Buscopan, try to take your medicine at a time when you can sit or lie down when the symptoms are worst. It may also help to cut down on alcohol, smoking, caffeine and big meals, as these can make the problem worse. If you're still having symptoms after a week, speak to your doctor. You may need to change to a different type of medicine.

9. Pregnancy and breastfeeding

Buscopan is not thought to be harmful in pregnancy. However, because there is only very limited information on its use in pregnancy, it's not generally recommended.

If you think you need to take Buscopan in pregnancy, talk to your doctor of pharmacist who will help you decide, or may recommend other medicines for you.

Buscopan and breastfeeding

Buscopan is not usually recommended while breastfeeding. However, some people may still need it. It's better to only take occasional doses or only take it for a short time.

It's not known how much Buscopan gets into breast milk, but it's likely to be a small amount. Buscopan may also reduce the amount of milk you produce.

If you're breastfeeding or planning to breastfeed, talk to your doctor or pharmacist, as other medicines might be better while you're breastfeeding. If they say it's OK for you to keep taking Buscopan, monitor your baby for possible side effects, such as sleepiness, constipation, peeing less than usual and colic.

If your baby is not feeding as well as usual, or you have any other concerns about your baby while you're breastfeeding, talk to your doctor, pharmacist, health visitor or midwife.


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For more information about how Buscopan can affect you and your baby during pregnancy, read this leaflet on the Best Use of Medicines in Pregnancy (BUMPS) website.


11. Cautions with other medicines

Some medicines and Buscopan can affect each other and increase the chances of you having side effects.

Do not take Buscopan at the same time as some motion sickness medicines, such as domperidone and metoclopramide.

This is because they can cancel each other out and stop each other from working. Metoclopramide and domperidone increase the movement of the gut, whereas Buscopan reduces it.

Some medicines increase the risk of side effects if you take them at the same time as Buscopan, including:

Do not take Buscopan together with other irritable bowel syndrome (IBS) remedies, as they work in the same way. You're unlikely to get extra relief for your symptoms, and it may cause more side effects. Take only one IBS remedy, unless your doctor tells you to take more than one.

Mixing Buscopan with herbal remedies and supplements

There's not enough information to say that complementary medicines and herbal remedies or supplements are safe to take with Buscopan.

They're not tested in the same way as pharmacy and prescription medicines. They're generally not tested for the effect they have on other medicines.


12. Common questions about Buscopan

Page last reviewed: 14/10/2021
Next review due: 14/10/2024