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If you have acute myeloid leukaemia (AML), you may experience complications. These can be caused by the condition itself, although they can also occur as a side effect of treatment.

Weakened immune system

Having a weakened immune system is a common complication of AML.

Even if your blood is restored to normal working order with treatment, many of the medications that are used to treat AML can temporarily weaken your immune system.

This means you're more vulnerable to developing an infection, and any infection you develop could be more serious than usual.

Complications arising from infection are very common in people with AML. But if treated early, nearly all infections respond to appropriate treatment.

You may be advised to:

Report any possible symptoms of an infection to your treatment unit immediately as prompt treatment may be needed to prevent complications.

Symptoms of an infection can include:


If you have AML, you might bleed and bruise more easily because of the low levels of platelets (clot-forming cells) in your blood. Bleeding may also be excessive.

People with advanced AML are more vulnerable to excessive bleeding inside their body.

Serious bleeding can occur:

All these types of haemorrhage should be regarded as medical emergencies.

Dial 999 immediately and ask for an ambulance if you think a haemorrhage is occurring.


Many of the treatments that are used to treat AML can cause infertility. This is often temporary, but in some cases can be permanent.

People particularly at risk of permanent infertility are those who have received high doses of chemotherapy and radiotherapy in preparation for a bone marrow or stem cell transplant.

Your treatment team can talk to you about the risk of infertility in your specific circumstances.

It may be possible to do things to help keep your fertility before you begin your treatment.

For example, men can have their sperm samples stored. Women can have eggs or fertilised embryos stored, which can then be placed back into their womb following treatment.

But as AML is an aggressive condition that develops rapidly, there may not always be time to do this before treatment needs to start.